A systematic review of the diagnostic accuracy of volatile organic compounds in airway diseases and their relation to markers of type-2 inflammation.

Wadah IbrahimSushiladevi NatarajanMichael J WildeRebecca CordellPaul S MonksNeil GreeningChristopher E BrightlingRachael Andrea EvansSalman Siddiqui

Published in: ERJ open research (2021)

Breath VOCs show promise as diagnostic biomarkers of airway diseases and for type-2 inflammation profiling. However, future studies should focus on transparent reporting of diagnostic accuracy and multivariate models and continue to focus on chemical identification of volatile metabolites.

Keyphrases

oxidative stress
single cell
current status
adverse drug
machine learning
data analysis
gas chromatography
bioinformatics analysis
liquid chromatography