Do germline genetic variants influence surgical outcomes in drug-resistant epilepsy?

Paula MarquesPatrick B MoloneyCaihong JiQuratulain Zulfiqar AliArchana RameshDavid B GoldsteinKaren BarbozaIlakkiah ChandranMarlene RongArunan SelvarajahFarah QaiserVictor S T LiraTaufik A ValianteOrrin DevinskyChantal DepondtTerence O'BrienPiero PeruccaArjune SenPatricia DuganTristan T SandsNorman DelantyDanielle M Andrade

Published in: Epilepsy research (2024)

Genomic findings, including a channelopathy diagnosis, should not preclude presurgical evaluation or epilepsy surgery, and appropriately selected cases may have good surgical outcomes. Prospective registries of patients with monogenic epilepsies who undergo epilepsy surgery can provide additional insights on outcomes.

Keyphrases

drug resistant
minimally invasive
coronary artery bypass
multidrug resistant
acinetobacter baumannii
dna repair
temporal lobe epilepsy
type diabetes
gene expression
copy number
percutaneous coronary intervention
coronary artery disease
dna damage
dna methylation