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Genetic Polymorphisms of Toll-like receptors 2 and 9 as Susceptibility Factors for the Development of Ankylosing Spondylitis and Psoriatic Arthritis.

Camila F Oliveira-ToréAmarilis Giaretta de MoraesGabriela F MartinezJanisleya S F NevesLuciana C MacedoMarco A Rocha-LouresMarília G QuirinoHugo Vicentin AlvesAna Maria SellJeane Eliete Laguila Visentainer
Published in: Journal of immunology research (2019)
The polymorphism rs5743708 for the TLR2 and the rs187084_rs5743836 TLR9 haplotypes appear to be involved in the development of clinical forms of SpA and can be a possible therapeutic target for the spondyloarthritis.
Keyphrases
  • ankylosing spondylitis
  • disease activity
  • toll like receptor
  • inflammatory response
  • rheumatoid arthritis
  • immune response
  • systemic lupus erythematosus
  • nuclear factor