The impact of sarcopenia and acute muscle mass loss on long-term outcomes in critically ill patients with intra-abdominal sepsis.
Michael C CoxMatthew BoothGabriela GhitaZhongkai WangAnna GardnerRussell B HawkinsDijoia B DardenChristiaan LeeuwenburghLyle L MoldawerFrederick A MoorePhilip A EfronSteven AntonScott C BrakenridgePublished in: Journal of cachexia, sarcopenia and muscle (2021)
Critically ill patients have an acute and persistent loss of muscle mass after intra-abdominal sepsis, which is associated with decreased health-related quality of life and physical function at 3 months. However, pre-existing sarcopenia, rather than persistent acute muscle mass loss at 3 months after sepsis, is independently associated with poor long-term functional status and increased 1 year mortality.