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The impact of sarcopenia and acute muscle mass loss on long-term outcomes in critically ill patients with intra-abdominal sepsis.

Michael C CoxMatthew BoothGabriela GhitaZhongkai WangAnna GardnerRussell B HawkinsDijoia B DardenChristiaan LeeuwenburghLyle L MoldawerFrederick A MoorePhilip A EfronSteven AntonScott C Brakenridge
Published in: Journal of cachexia, sarcopenia and muscle (2021)
Critically ill patients have an acute and persistent loss of muscle mass after intra-abdominal sepsis, which is associated with decreased health-related quality of life and physical function at 3 months. However, pre-existing sarcopenia, rather than persistent acute muscle mass loss at 3 months after sepsis, is independently associated with poor long-term functional status and increased 1 year mortality.
Keyphrases
  • liver failure
  • respiratory failure
  • acute kidney injury
  • intensive care unit
  • septic shock
  • aortic dissection
  • drug induced
  • skeletal muscle
  • type diabetes
  • cardiovascular disease
  • coronary artery disease