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Exploring the cytotoxicity and anticancer effects of doxycycline and azithromycin on human glioblastoma multiforme cells.

Siti Nazihahasma HassanAbdul Aziz Mohamed YusoffZamzuri IdrisNorhanani Mohd RedzwanFarizan Ahmad
Published in: Neurological research (2021)
The antiproliferative and apoptosis-inducing activity exhibited by both antibiotics against U87 cells demonstrates their potential as a likely alternative to combat GBM. It would be interesting to find out more about their molecular players and cytotoxic effects in different types of GBM cells, including glioma stem cells (GSCs).
Keyphrases
  • cell cycle arrest
  • induced apoptosis
  • stem cells
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • pi k akt
  • risk assessment
  • mesenchymal stem cells
  • cell proliferation