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Impaired topology and connectivity of grey matter structural networks in major depressive disorder: evidence from a multi-site neuroimaging data-set.

Jing-Yi LongKun QinNanfang PanWen-Liang FanYi Li
Published in: The British journal of psychiatry : the journal of mental science (2024)
Based on this high-powered data-set, we identified reliable patterns of impaired topology and connectivity of individualised SCN in MDD and relevant subtypes, which adds to the current understanding of neuropathology of MDD and might guide future development of diagnostic and therapeutic markers.
Keyphrases
  • major depressive disorder
  • bipolar disorder
  • white matter
  • electronic health record
  • resting state
  • functional connectivity
  • big data
  • multiple sclerosis
  • current status
  • machine learning