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Cytokine changes during immune-related adverse events and corticosteroid treatment in melanoma patients receiving immune checkpoint inhibitors.

Kevin TyanJoanna BaginskaMartha BrainardAnita Giobbie-HurderMariano SevergniniMichael ManosRizwan HaqElizabeth I BuchbinderPatrick A OttF Stephen HodiOsama E Rahma
Published in: Cancer immunology, immunotherapy : CII (2021)
Baseline levels of certain cytokines correlate with specific irAEs in melanoma patients receiving ICIs. irAEs drive a concordant pattern of cytokine fold-change, which is disrupted by corticosteroid treatment.
Keyphrases
  • combination therapy
  • basal cell carcinoma