Individual participant data validation of the PICNICC prediction model for febrile neutropenia.

Robert S PhillipsJessica Elizabeth MorganGabrielle M HaeuslerRichard D Rileynull null

Published in: Archives of disease in childhood (2019)

This meta-analysis shows the PICNICC model should not be used at admission to predict MDI. Further work should focus on validating alternative prediction models. Validation across multiple cohorts from diverse locations is essential before widespread clinical adoption of such rules to avoid overtreating or undertreating children with fever with neutropenia.

Keyphrases

chemotherapy induced
systematic review
electronic health record
emergency department
young adults
meta analyses
big data
urinary tract infection
machine learning
case control
deep learning