Paladin, overexpressed in colon cancer, is required for actin polymerisation and liver metastasis dissemination.
Gilles RademakerBrunella CostanzaSebastien Pyr Dit RuysRaphaël PeifferFerman AgirmanNaïma MaloujahmoumDidier VertommenAndrei TurtoiAkeila BellahcèneVincent CastronovoOlivier PeulenPublished in: Oncogenesis (2022)
Paladin is an undervalued protein in oncology. This study highlights for the first time that, paladin is participating in actin cytoskeleton remodelling and is required for efficient cancer cell migration.