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In Silico and In Vivo Studies of β-Sitosterol Nanoparticles as a Potential Therapy for Isoprenaline-Induced Cognitive Impairment in Myocardial Infarction, Targeting Myeloperoxidase.

Partha Saradhi TallapalliYennam Dastagiri ReddyDeepak A YaraguppiSurya Prabha MatangiRanadheer Reddy ChallaBhaskar VallamkondaSheikh Fayaz AhmadHaneen A Al-MazrouaMithun RudrapalD S N B K PrasanthPraveen Kumar Pasala
Published in: Pharmaceuticals (Basel, Switzerland) (2024)
Compared with BET treatment, BETNs were more effective in improving cognitive impairment, oxidative damage, and inflammation in MI rats, suggesting its potential in treating cognitive dysfunction and associated pathological changes in MI.
Keyphrases
  • cognitive impairment
  • oxidative stress
  • diabetic rats
  • heart failure
  • high glucose
  • molecular docking
  • drug induced
  • human health
  • drug delivery
  • replacement therapy
  • atrial fibrillation