miRNAs and target genes in the blood as biomarkers for the early diagnosis of Parkinson's disease.

Xiaoting LiuJinhu ChenTianyuan GuanHui YaoWenpei ZhangZhenlong GuanYanqin Wang

Published in: BMC systems biology (2019)

This study provides data of potential biomarkers and therapeutic targets for PD diagnosis and treatment. Among them, hsa-miR-142 is a critical miRNA in the PD network, and may be involved in PD progression by regulating GNAQ, TMTC2, BEND2, and KYNU.

Keyphrases

cell proliferation
electronic health record
genome wide
machine learning
gene expression
dna methylation
deep learning
transcription factor
bioinformatics analysis
genome wide analysis