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Identification of key candidate targets and pathways for the targeted treatment of leukemia stem cells of chronic myelogenous leukemia using bioinformatics analysis.

Huayao LiLijuan LiuJing ZhuangCun LiuChao ZhouJing YangChundi GaoGongxi LiuChanggang Sun
Published in: Molecular genetics & genomic medicine (2019)
We identified key candidate targets and pathways for CML LSCs through bioinformatics methods, which improves our understanding of the molecular mechanisms of CML LSCs. These candidate genes and pathways may be therapeutic targets for CML LSCs.
Keyphrases
  • bioinformatics analysis
  • stem cells
  • acute myeloid leukemia
  • chronic myeloid leukemia
  • bone marrow
  • cancer therapy
  • mesenchymal stem cells
  • combination therapy
  • drug induced