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Phase 1 Study to Evaluate the Safety of Reducing the Prophylactic Dose of Dexamethasone around Docetaxel Infusion in Patients with Prostate and Breast Cancer.

Rieneke T LugtenbergStefanie de GrootDanny HoutsmaVincent O DezentjéAnnelie J E VulinkMaarten J FischerJohanneke E A PortieljeJacobus J M van der HoevenAndré B P van KuilenburgHanno PijlJudith R Kroep
Published in: Cancers (2023)
It seems that the prophylactic dose of dexamethasone around docetaxel infusion can be safely reduced with respect to the occurrence of grade III/IV HSRs or the fluid retention syndrome.
Keyphrases
  • low dose
  • high dose
  • prostate cancer
  • locally advanced
  • risk assessment
  • open label
  • benign prostatic hyperplasia
  • squamous cell carcinoma
  • young adults
  • radiation therapy
  • clinical trial
  • breast cancer risk