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Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors.

Giuseppe LambertiC CeccarelliN BrighiI MaggioD SantiniC MosconiC RicciG BiascoDavide Campana
Published in: Gastroenterology research and practice (2017)
With the limits of retrospective data, activation of m-TOR is correlated with advanced disease at diagnosis and with shorter disease-free survival after R0 resection. Validation through prospective studies is needed.
Keyphrases
  • prognostic factors
  • neuroendocrine tumors
  • electronic health record
  • big data
  • machine learning
  • solid phase extraction
  • high resolution
  • mass spectrometry
  • data analysis
  • liquid chromatography