Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors.

Giuseppe LambertiC CeccarelliN BrighiI MaggioD SantiniC MosconiC RicciG BiascoDavide Campana

Published in: Gastroenterology research and practice (2017)

With the limits of retrospective data, activation of m-TOR is correlated with advanced disease at diagnosis and with shorter disease-free survival after R0 resection. Validation through prospective studies is needed.

Keyphrases

prognostic factors
neuroendocrine tumors
electronic health record
big data
machine learning
solid phase extraction
high resolution
mass spectrometry
data analysis
liquid chromatography