Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors.
Giuseppe LambertiC CeccarelliN BrighiI MaggioD SantiniC MosconiC RicciG BiascoDavide CampanaPublished in: Gastroenterology research and practice (2017)
With the limits of retrospective data, activation of m-TOR is correlated with advanced disease at diagnosis and with shorter disease-free survival after R0 resection. Validation through prospective studies is needed.