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Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics.

Satu OltedalIvar SkalandJodi Maple-GrødemKjersti TjensvollEmiel A M JanssenBjørnar GiljeRune SmaalandReino HeikkiläOddmund Nordgård
Published in: BMC gastroenterology (2018)
Functional analyses of the novel PHGR1 mRNA and protein suggest an essential role in gastrointestinal epithelium and a clinical application in detection of colorectal cancer lymph node metastases.
Keyphrases
  • lymph node
  • binding protein
  • protein protein
  • amino acid
  • neoadjuvant chemotherapy
  • genome wide
  • squamous cell carcinoma
  • risk assessment
  • gene expression
  • dna methylation
  • climate change
  • human health
  • real time pcr