Immune monitoring-guided vs fixed duration of antiviral prophylaxis against cytomegalovirus in solid-organ transplant recipients. A Multicenter, Randomized Clinical Trial.
Oriol ManuelMirjam LaagerCédric HirzelDionysios NeofytosLaura N WaltiGideon HoengerIsabelle BinetAurelia SchnyderSusanne StampfMichael KollerMatteo MombelliMin Jeong KimMatthias HoffmannKatrin KoenigChristoph HessAnne-Valérie BurgenerPietro E CippàKerstin HübelThomas F MuellerDaniel SidlerSuzan DahdalFranziska Suter-RinikerJean VillardAndrea ZbindenGiuseppe PantaleoNasser SemmoKarine HadayaNatalia EnríquezPascal R MeylanMarc FroissartDela GolshayanThomas FehrUyen Huynh-DoManuel PascualChristian Van DeldenHans H HirschPeter JüniNicolas J Muellernull nullPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
Immune monitoring resulted in a significant reduction of antiviral prophylaxis, but we were unable to establish noninferiority of this approach on the co-primary endpoint of CMV infection.
Keyphrases