MRI measures of hypothalamic injury are associated with glucagon-like peptide-1 receptor agonist treatment response in people with hypothalamic obesity.
Francisco A PerezClinton ElfersJack A YanovskiAshley H ShoemakerM Jennifer AbuzzahabChristian L RothPublished in: Diabetes, obesity & metabolism (2021)
In people with HO, greater hypothalamic damage as determined by MRI, in particular MB injury, is associated with greater reductions in adiposity following GLP-1RA treatment.
Keyphrases
- contrast enhanced
- insulin resistance
- magnetic resonance imaging
- weight gain
- metabolic syndrome
- diffusion weighted imaging
- rheumatoid arthritis
- type diabetes
- weight loss
- computed tomography
- high fat diet induced
- magnetic resonance
- adipose tissue
- disease activity
- combination therapy
- ankylosing spondylitis
- systemic lupus erythematosus
- replacement therapy
- smoking cessation