Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice.

Pamela BoufleurJuliana Mozer ScianiMauricio GoldfederFernanda FariaVânia BrancoAna Marisa Chudzinski-Tavassi

Published in: European journal of drug metabolism and pharmacokinetics (2019)

These findings suggest that amblyomin-X is rapidly distributed to the tissues, metabolized by the liver or even kidneys, and eliminated in urine in healthy mice. There is no accumulation in any organ.

Keyphrases

high fat diet induced
gene expression
type diabetes
computed tomography
pet imaging
protein protein
amino acid
small molecule
binding protein