Pulsed electromagnetic fields potentiate bone marrow mesenchymal stem cell chondrogenesis by regulating the Wnt/β-catenin signaling pathway.

Kangping SongJing HuMing YangYong XiaChengqi HeYonghong YangSi-Yi Zhu

Published in: Journal of translational medicine (2024)

PEMFs at 75 Hz and 3 mT are optimal in inducing early-stage chondrogenic differentiation of BMSCs. The induction and chondroprotective effects of PEMFs are mediated by sFRP3 and Wnt/β-catenin signaling, irrespective of inflammatory conditions.

Keyphrases

mesenchymal stem cells
bone marrow
early stage
umbilical cord
cell proliferation
stem cells
high frequency
cell therapy
sentinel lymph node
squamous cell carcinoma
lymph node