Timing of administration of antenatal magnesium sulfate and umbilical cord blood magnesium levels in preterm babies.
Adam J ReynoldsSuzanne SlatterySusan ByrneElaine NearySieglinde MüllersEtaoin KentFergal D MaloneAfif El-KhuffashCliona McGarveyBreda C HayesPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2017)
In the bolus only group, the highest mean Mg levels were observed with administration 1-2 hours before delivery, but the findings were not statistically significant. Compared to the rest of the cohort, higher Mg levels were found when a bolus was followed by an infusion. Following a MgSO4 bolus, some growth restricted extremely preterm babies may have higher Mg levels than would be otherwise expected.