Survival Analysis of Metastatic Early-Onset Colorectal Cancer Compared to Metastatic Average-Onset Colorectal Cancer: A SEER Database Analysis.
Antoine Jeri-YabarLiliana Vittini-HernandezSebastian Prado-NuñezSirish DharmapuriPublished in: Cancers (2024)
Most patients with mEO-CRC fall within the range of 45 to 49 years of age. Patients with mEO-CRC were more likely to receive cancer-directed therapy (including chemotherapy and radiotherapy) and had better OS and CSS than those with mAO-CRC. This is likely attributable to the better performance status, fewer comorbidities, and better tolerance to cancer-directed therapy in mEO-CRC patients. The factors associated with worse OS and CSS were age > 50 years, mucinous adenocarcinoma, male sex, and no surgical treatment.
Keyphrases
- early onset
- squamous cell carcinoma
- papillary thyroid
- locally advanced
- end stage renal disease
- small cell lung cancer
- squamous cell
- late onset
- chronic kidney disease
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- lymph node metastasis
- prognostic factors
- radiation induced
- childhood cancer
- cell therapy
- mesenchymal stem cells
- adverse drug
- young adults
- rectal cancer
- smoking cessation
- high grade