Investigating the Long-term Effect of Pregnancy on the Course of Multiple Sclerosis Using Causal Inference.
Antoine GavoilleFabien RollotRomain CaseyMarc DebouverieEmmanuelle Le PageJonathan CironJerome De SezeAurélie RuetElisabeth MaillartPierre LabaugeHelene ZephirCaroline PapeixGilles DeferChristine Lebrun-FrénayThibault MoreauDavid Axel LaplaudEric BergerBruno StankoffPierre ClavelouEric ThouvenotOlivier HeinzlefJean PelletierAbdullatif Al KhedrOlivier CasezBertrand BourrePhilippe CabreAbir WahabLaurent MagyJean-Philippe CamdessancheAude MauroussetSolène MoulinNasr Haifa BenDalia Dimitri BoulosKarolina HankiewiczJean-Philippe NeauCorinne PottierChantal NifleMuriel RabilloudFabien SubtilSandra Vukusicnull nullPublished in: Neurology (2022)
Using a causal inference approach, we found no evidence of significantly deleterious or beneficial long-term effects of pregnancy on disability. The beneficial effects found in other studies were probably related to a reverse causation bias.