Proteomic and genomic profiling of plasma exosomes from patients with ankylosing spondylitis.

Fataneh TavasolianStarlee LivelyChiara PastrelloMichael TangMelissa LimAddison PachecoZoya QaiyumEnoch YauZeynep BaskurtIgor JurisicaMohit KapoorRobert Davies Inman

Published in: Annals of the rheumatic diseases (2023)

Individuals with AS have different immunological and genetic profiles, as determined by evaluating the exosomes of these patients. The inhibitory effect of exosomes on Treg in AS suggests a mechanism contributing to chronically activated T cells in this disease.

Keyphrases

ankylosing spondylitis
mesenchymal stem cells
stem cells
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
rheumatoid arthritis
copy number
disease activity
dna methylation