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Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development.

Evie StergiakouliGeorge Davey SmithJoanna MartinDavid H SkuseWolfgang ViechtbauerSusan M RingAngelica RonaldDavid E EvansSimon E FisherAnita ThaparBeate St Pourcain
Published in: Molecular autism (2017)
In the general population, genetic aetiologies between social-communication difficulties and ADHD symptoms are shared throughout child and adolescent development and may implicate similar biological pathways that co-vary during development. Within both the ASD and the ADHD dimension, population-based traits are also linked to clinical disorder, although much larger clinical discovery samples are required to reliably detect cross-dimensional trait-disorder relationships.
Keyphrases
  • attention deficit hyperactivity disorder
  • autism spectrum disorder
  • mental health
  • genome wide
  • working memory
  • young adults
  • intellectual disability
  • healthcare
  • dna methylation
  • depressive symptoms