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Establishing a genetic link between FTO and VDR gene polymorphisms and obesity in the Emirati population.

Saad Mahmud KhanSarah El Hajj ChehadehMehera AbdulrahmanWael OsmanHabiba S AlSafar
Published in: BMC medical genetics (2018)
Our study findings indicate that the minor allele A of the rs9939609 has a significant association with increasing BMI values. Moreover, our findings support the fact that increasing BMI is associated with increasing risks of other comorbidities such as higher blood pressure, poorer glycemic control, and higher triglycerides. In addition, physical activity was found to attenuate the effect of the "AA" genotype on the predisposition to higher BMI values.
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