Neglected Mendelian causes of stroke in adult Chinese patients who had an ischaemic stroke or transient ischaemic attack.
Wei LiHao LiChaoxia LuJialu ZhaoHuichun XuZhe XuBraxton MitchellYong JiangHong-Qiu GuQin XuAnxin WangXia MengJinxi LinJing JingZixiao LiWanlin ZhuZhigang LiangMengxing WangYong-Jun WangPublished in: Stroke and vascular neurology (2023)
The rate of monogenic cause of stroke was 2.2% after reviewing the clinical phenotype. Possible reasons that Mendelian causes of stroke may be missed in adult patients who had an ischaemic stroke/TIA include a late onset of stroke symptoms, combination with common vascular risks and the absence of a prominent family history.