Embryonic stem cell-derived extracellular vesicles promote the recovery of kidney injury.

Lu YuSiying LiuChen WangChuanyu ZhangYajie WenKaiyue ZhangShang ChenHaoyan HuangYue LiuLingling WuZhongchao HanXiangmei ChenZongjin LiNa Liu

Published in: Stem cell research & therapy (2021)

ESC-EVs significantly promote the physiological repair and inhibit the pathological repair after AKI, enabling restoration of the structure and function of the damaged kidney. This strategy might emerge as a novel therapeutic strategy for ESC clinical application.

Keyphrases

stem cells
acute kidney injury
mesenchymal stem cells
bone marrow
cell therapy