Chromosomal abnormalities detected by karyotyping and microarray analysis in twins with structural anomalies.

Lin LiZ HeX HuangS LinJ WuL HuangY WanQ Fang

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2020)

Dichorionic twins with structural anomalies have a higher risk of chromosomal abnormalities, especially aneuploidies, than do monochorionic twins. The incremental diagnostic yield of CMA over karyotyping seems to be lower (2.0%) in twins than that reported in singleton pregnancy. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

gestational age
preterm birth
birth weight
copy number
pregnant women
systematic review
body mass index
dna methylation
physical activity