Proteomic Analysis of Mouse Kidney Tissue Associates Peroxisomal Dysfunction with Early Diabetic Kidney Disease.
Aggeliki TsergaDespoina PouloudiJean Sébastien Saulnier-BlacheRafael StroggilosIrene TheochariHarikleia GakiopoulouHarald MischakJerome ZoidakisJoost Peter SchanstraAntonia VlahouManousos MakridakisPublished in: Biomedicines (2022)
Our study shows an extensive differential expression of peroxisomal proteins in the early stages of DKD that persists regardless of the disease severity, providing new perspectives and potential markers of diabetic kidney dysfunction.