Prognostic Role of Preoperative Vascular Cell Adhesion Molecule-1 Plasma Levels in Urothelial Carcinoma of the Bladder Treated With Radical Cystectomy.

Keiichiro MoriVictor M SchuettfortSatoshi KatayamaEkaterina LaukhtinaBenjamin PradereFahad QuhalReza Sari MotlaghHadi MostafaeiNico C GrossmannPawel RajwaJeremy Yc TeohIrene ReschHarun FajkovicMarco MoschiniDavid D'andreaMohammad AbufarajPierre I KarakiewiczYair LotanDouglas ScherrShin EgawaEva CompératShahrokh F Shariatnull null

Published in: Annals of surgical oncology (2022)

Elevated plasma VCAM-1 was associated with biologically and clinically aggressive UCB disease features. After validation, preoperative VCAM-1 may serve as a biomarker to help identify patients likely to benefit from intensified/multimodal therapy. In addition, VCAM-1 improved the discriminatory power of predictive/prognostic models and can be used to refine personalized clinical decision-making.

Keyphrases

cell adhesion
decision making
newly diagnosed
end stage renal disease
patients undergoing
ejection fraction
spinal cord injury
peritoneal dialysis
prognostic factors
stem cells
pain management
patient reported
urinary tract