Association between alcohol use disorders and dementia in 262,703 dementia-free Finnish adults: Is cardiovascular disease a mediator?

Yaoyue Hu Kaarina KorhonenPeng LiMartin Bobak Pekka T MartikainenMaarten J Bijlsma

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2022)

AUD increased dementia risk, particularly the risk of early-onset dementia. This elevated risk of dementia associated with AUD was not mediated by CVD. Clinicians should consider the increased risk of dementia in management of middle-aged and older adults with a history and/or current AUD.

Keyphrases

metabolic syndrome
mild cognitive impairment
cognitive impairment
early onset
cardiovascular disease
late onset
type diabetes
physical activity
coronary artery disease
cardiovascular events