The Ala307Thr polymorphism of the follicle-stimulating hormone receptor (FSHR) gene is associated with the dose of recombinant FSH received during IVF/ICSI treatment.

Felipe DieamantClaudia Guilhermino PetersenLaura Diniz VagniniBruna PetersenJuliana RicciAndreia NicolettiCamila ZamaraAntonio Helio OlianiJoao Batista A OliveiraJosé G Franco

Published in: JBRA assisted reproduction (2023)

The Ala/Ala genotype was associated with the use of higher doses of recombinant FSH (r-FSH), suggesting that homozygosis of this allelic variant (Ala) provides lower sensitivity to r-FSH.

Keyphrases

pregnancy outcomes
cell free
copy number
pregnant women
gene expression