Hepatoprotective effect of Holothuria leucospilota methanolic extract on dimethyl nitrosamine-induced hepatotoxicity in rats.

Fatemeh Dejan Amineh Daneshi Javad Rajabi AslaniNasrollah AhmadiNarges Eskandari RoozbahaniElaham RahmanianReza BehmaneshHamid Reza Gheisari

Published in: Animal models and experimental medicine (2024)

We demonstrated the hepatoprotective effect of H. leucospilota on DMN-induced liver damage in rats using biochemical and histological parameters and ultrasonography. More additional research (in silico or in vitro) is needed to find the exact mechanism and the main biological compound in H. leucospilota.

Keyphrases

high glucose
diabetic rats
drug induced
oxidative stress
magnetic resonance imaging
computed tomography