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Connectomic Profiles and Cognitive Trajectories After Epilepsy Surgery in Children.

Olivia N ArskiDaniel J MartireJulia M YoungSimeon M WongHrishikesh SureshElizabeth N KerrAyako OchiHiroshi OtsuboRoy SharmaElysa WidjajaO Carter SneadPuneet JainElizabeth J DonnerMary Lou SmithGeorge M Ibrahim
Published in: Neurology (2022)
Here, we report that connectomes characterized by diffuse connectivity, reminiscent of developmentally immature networks, are associated with lower preoperative cognition and postoperative cognitive improvement. These findings provide a potential means to understand neurocognitive function in children with temporal lobe epilepsy and expected changes postoperatively.
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