Phloroglucinol Derivatives from Myrtus communis 'Variegata' and Their Antibacterial Activities.
Yan WuMing ChenWen-Jing WangNi-Ping LiWen-Cai YeLei WangPublished in: Chemistry & biodiversity (2020)
Myrtucomvalones D-F, three new triketone-phloroglucinol-triketone adducts, and three known ones (myrtucommulone E, myrtucommulone D and callistenone D) were obtained from Myrtus communis 'Variegata'. Myrtucomvalone D is a pair of enantiomers which was further resolved into (+)-myrtucomvalone D and (-)-myrtucomvalone D by chiral HPLC. Their structures and complete stereochemistry were established from interpretation of NMR and crystallographic data and chemical calculations. Myrtucomvalone F, myrtucommulone D and callistenone D showed significant antibacterial activities.
Keyphrases
- high resolution
- silver nanoparticles
- ms ms
- capillary electrophoresis
- magnetic resonance
- density functional theory
- simultaneous determination
- mass spectrometry
- electronic health record
- molecular dynamics
- anti inflammatory
- molecular dynamics simulations
- essential oil
- wound healing
- high performance liquid chromatography
- solid state
- ionic liquid
- solid phase extraction
- data analysis
- monte carlo
- deep learning
- artificial intelligence
- structure activity relationship