The Prognostic Value of Lung Injury and Fibrosis Markers, KL-6, TGF-β1, FGF-2 in COVID-19 Patients.

Hazan KaradenizAslıhan Avanoğlu GülerHasan Selçuk ÖzgerPınar Aysert YıldızGonca ErbaşGülendam BozdayıTuba Deveci BulutÖzlem GülbaharDilek YaparHamit KüçükMehmet Akif ÖztürkAbdurrahman Tufan

Published in: Biomarker insights (2022)

Serum KL-6 levels were significantly elevated at the diagnosis of COVID-19 and correlated well with the other traditional prognostic inflammatory markers. Serum levels of principal fibrosis mediators, TGF-β1, FGF-2, were not elevated at diagnosis of COVID-19, therefore did not help to anticipate long term prognosis.

Keyphrases

sars cov
coronavirus disease
transforming growth factor
respiratory syndrome coronavirus
epithelial mesenchymal transition
signaling pathway