Effects of piperacillin/tazobactam or cefepime on folinate dose in patients receiving high-dose methotrexate: A retrospective cohort study using Japanese administrative claims data.

Shota Kadomura Shungo Imai Kenji Momo Yuki Sato Hitoshi KashiwagiTatsuya ItohMitsuru Sugawara Yoh Takekuma

Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2021)

Our findings revealed that PIPC/TAZ did not necessarily cause a delay in MTX clearance during HD-MTX therapy. Moreover, the co-administration of CFPM with HD-MTX did not affect MTX clearance.

Keyphrases

high dose
low dose
stem cell transplantation
health insurance
electronic health record
gram negative
multidrug resistant
data analysis
smoking cessation