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Incidence and clinical significance of 491 known fusion genes in a large cohort of Japanese patients with colorectal cancer.

Kenji NanishiHitoshi HinoKeiichi HatakeyamaAkio ShiomiHiroyasu KagawaShoichi ManabeYusuke YamaokaTakeshi NagashimaKeiichi OhshimaKenichi UrakamiYasuto AkiyamaKen Yamaguchi
Published in: International journal of clinical oncology (2023)
Broad screening for fusion genes showed that RSPO fusions were the most common in colorectal cancer, with an incidence of 1.5%. RSPO fusions may be clinically significant in identifying patients at a high risk of recurrence who would be responsive to specific treatments.
Keyphrases
  • risk factors
  • genome wide
  • bioinformatics analysis
  • genome wide identification
  • cancer therapy
  • dna methylation
  • genome wide analysis
  • transcription factor