Incidence and clinical significance of 491 known fusion genes in a large cohort of Japanese patients with colorectal cancer.
Kenji NanishiHitoshi HinoKeiichi HatakeyamaAkio ShiomiHiroyasu KagawaShoichi ManabeYusuke YamaokaTakeshi NagashimaKeiichi OhshimaKenichi UrakamiYasuto AkiyamaKen YamaguchiPublished in: International journal of clinical oncology (2023)
Broad screening for fusion genes showed that RSPO fusions were the most common in colorectal cancer, with an incidence of 1.5%. RSPO fusions may be clinically significant in identifying patients at a high risk of recurrence who would be responsive to specific treatments.