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Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke.

Pascal M JabbourRitam GhoshAdam LeiboldMichael B AveryRichard F SchmidtThana TheofanisNikolaos MouchtourisLucas PhilippStephen C PeiperZi-Xuan WangFred RinconStavropoula I TjoumakarisPascal JabbourRobert H RosenwasserM Reid Gooch
Published in: Journal of neurology, neurosurgery, and psychiatry (2020)
Our report shows that patients' CSF may be devoid of viral particles even when they test positive for COVID-19 on a nasal swab. Whether SARS-CoV-2 is present in CSF may depend on the systemic disease severity and the degree of the virus' nervous tissue tropism and should be examined in future studies.
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