Peppermint and caraway oils have muscle inhibitory and pro-secretory activity in the human intestine in vitro.
Dagmar KruegerStefanie SchäuffeleFlorian ZellerIhsan Ekin DemirJörg TheisenKlaus MichelMichael SchemannPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)
The findings revealed a strong muscle inhibitory and pro-secretory action of peppermint and caraway oils at clinically relevant concentrations. Both actions were nerve-independent. The inhibition of contractility was mediated by inhibition of L-type calcium channels. The effects on muscle and epithelial activity may contribute to the beneficial effects observed in patients with FGD.