Whole blood thrombin generation profiles of patients with cirrhosis explored with a near patient assay.
Jun WanLara N RobertsWasiliki HendrixJoke KoningsTsai-Wing OwLiane RabinowichOmar BarboutiBas de LaatRoopen AryaVishal C PatelMark RoestJ P LuyendykWilliam BernalPublished in: Journal of thrombosis and haemostasis : JTH (2020)
The WB-TG assay shows a normal to hypocoagulable state in patients with cirrhosis with a decreased anticoagulant activity of TM compared to plasma-TG. The clinical value of this assay needs further validation.