CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs.

Gan XiongZhi ChenQianwen LiuFang PengCaihua ZhangMaosheng ChengRongsong LingShuang ChenYu LiangDemeng Chen Qimin Zhou

Published in: Journal for immunotherapy of cancer (2024)

This study successfully elucidates the functional role of CD276 in ESCC. Our comprehensive analysis uncovers the significant role of CD276 in modulating immune surveillance mechanisms in ESCC, thereby suggesting that targeting CD276 might serve as a potential therapeutic approach for ESCC treatment.

Keyphrases

nk cells
public health
drug delivery
replacement therapy
cell migration