Fu-Fang-Jin-Qian-Cao herbal granules protect against the calcium oxalate-induced renal EMT by inhibiting the TGF-β/smad pathway.

Wen-Rui LiuHong-Tao LuTing-Ting ZhaoJia-Rong DingYa-Chen SiWei ChenJie-Bin HouSong-Yan GaoXin DongBing Yu Zhi-Yong GuoJian-Rao Lu

Published in: Pharmaceutical biology (2021)

FFJQC alleviated the CaOx-induced renal EMT and fibrosis by regulating TGF-β/smad pathway. Therefore, the FFJQC is an important traditional Chinese medicine for the treatment of CaOx-induced renal injury and fibrosis.

Keyphrases

epithelial mesenchymal transition
transforming growth factor
high glucose
diabetic rats
oxidative stress
endothelial cells
smoking cessation
replacement therapy
stress induced