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Sialic acid metabolism orchestrates transcellular connectivity and signalling in glioblastoma.

Ugne KuliesiuteKevin JosephJakob StraehleVidhya Madapusi RaviJan KueckelhausJasim Kada BenotmaneJunyi ZhangAndreas VlachosJuergen BeckOliver SchnellUrte NeniskyteDieter Henrik Heiland
Published in: Neuro-oncology (2023)
Our results indicate that sialic acid is essential for the establishment of GBM tumor and its cellular network. They highlight the importance of sialic acid for glioblastoma pathology and suggest that dynamics of sialylation have the potential to be targeted therapeutically.
Keyphrases
  • multiple sclerosis
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