The role of occlusion and micro-incontinence in the pathogenesis of penile lichen sclerosus: an observational study of pro-inflammatory cytokines' gene expression.

Mateusz Czajkowski Piotr Mieczyslaw Wierzbicki Anna Kotulak-Chrząszcz Katarzyna Czajkowska M Bolcewicz Jakub Kłącz K Kreft Anna Lewandowska Bogusław Nedoszytko Małgorzata Sokołowska-Wojdyło Zbigniew Kmieć Bogusław Nedoszytko Roman Janusz Nowicki Matuszewski Marcin

Published in: International urology and nephrology (2022)

Occlusion and irritating urine effect are associated with the clinical progression of penile LS with increased mRNA expression of IL-1A, INF-γ, and IL-6 pro-inflammatory cytokines in the foreskin.

Keyphrases

gene expression
anti inflammatory
dna methylation
radical prostatectomy
prostate cancer