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On inflammation-immunological balance theory-A critical apprehension of disease concepts around implants: Mucositis and marginal bone loss may represent normal conditions and not necessarily a state of disease.

Tomas AlbrektssonTorsten JemtJohan MölnePentti TengvallAnn Wennerberg
Published in: Clinical implant dentistry and related research (2018)
Implants survive in the body due to balanced defense reactions in form of chronic inflammation and activation of the innate immune system. Ten year results of oral and hip /knee implants are hence in the 90+ percentage region. Clinical problems may occur with bone resorption that in most cases is successfully counterbalanced by the defense/healing systems. However, in certain instances implant failure will ensue characterized by bacterial attacks and/or by reactivation of the immune system that now will act to remove the foreign bodies from the tissues.
Keyphrases
  • bone loss
  • soft tissue
  • oxidative stress
  • immune response
  • mental health
  • gene expression
  • total knee arthroplasty
  • radiation induced
  • total hip arthroplasty
  • radiation therapy
  • postmenopausal women
  • chemotherapy induced