Redifferentiation Therapy-Returning to Our Roots in a Post-Kinase Inhibitor World.

Maria E Cabanillas Naifa L Busaidy Steven I Sherman

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Radioactive iodine (RAI) treatment is an effective treatment for differentiated thyroid cancer (DTC); however, many patients are refractory. Using targeted drugs to reinduce RAI sensitivity ("redifferentiation therapy") has long been sought after as the holy grail in endocrine oncology. See related article by Weber et al., p. 4194.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
stem cells
peritoneal dialysis
patient reported outcomes