Neutrophil phenotypes in bronchial airways differentiate single from dual responding allergic asthmatics.
Nicole M D van der BurgHenning StenbergSandra EkstedtZuzana DiamantDaisy BornesundJaro AnkerstSusanna Kumlien GeorénLars-Olaf CardellLeif BjermerJonas S ErjefältEllen TufvessonPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2022)
DR have a more active airway neutrophil phenotype at baseline and a distinct neutrophil response to allergen challenge that may contribute to the development of an LAR. Therefore, neutrophil activity should be considered during targeted diagnosis and bio-therapeutic development for DR.
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