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Small molecules block the interaction between porcine reproductive and respiratory syndrome virus and CD163 receptor and the infection of pig cells.

Chang HuangDenzil BernardJiaqi ZhuRadha Charan DashAlexander ChuAlec KnuppAnna HakeyM Kyle HaddenAntonio GarmendiaYoung Tang
Published in: Virology journal (2020)
Our study identified a novel strategy to potentially prevent PRRSV infection in pigs by blocking the PRRSV-CD163 interaction with small molecules.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • nk cells
  • signaling pathway
  • cell death
  • endoplasmic reticulum stress
  • cell proliferation