Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States.
Sesh A SundararamanKaren L Hanze VillavicencioBrianne RoperZiyi WangAmy K F DavisJonathan A MayhewMichelle L WangNina L TangVijaya L SomaGail F ShustMargaret E FeeneyIndi TrehanJill E WeatherheadChandy C JohnJeffrey S GerberAudrey R Odom JohnPublished in: Journal of the Pediatric Infectious Diseases Society (2024)
Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however severe hemolysis requiring hospitalization or transfusion was rare. In children in the U.S. treated with artesunate, counseling and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.